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Does Epinephrine 03 Adults Interact with Levothyroxine?

Epinephrine 03 Adults and Levothyroxine have a major drug interaction according to U.S. FDA drug labeling data. Effects of epinephrine may be potentiated by levothyroxine sodium. The mechanism involves potentiation of epinephrine effects. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Epinephrine 03 Adults Class
alpha-Adrenergic Agonist
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Epinephrine 03 Adults and Levothyroxine occurs because potentiation of epinephrine effects. Clinically, this means effects of epinephrine may be potentiated by levothyroxine sodium. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.

What To Tell Your Doctor or Pharmacist

If you are taking Epinephrine 03 Adults and your doctor is considering prescribing Levothyroxine (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Epinephrine 03 Adults(Epinephrine 0.3 Adults)+💊 Levothyroxine(Thyro-Tabs)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
alpha-Adrenergic Agonist
Drug B class
—
Source
NLP:epinephrine 0.3 adults

What this means in plain English

Effects of epinephrine may be potentiated by levothyroxine sodium.

About Epinephrine 03 Adults and Levothyroxine

Epinephrine 03 Adults is an alpha-Adrenergic Agonist. Levothyroxine is also sold under the brand name Thyro-Tabs. Epinephrine 03 Adults is given by injection under the skin.

What the FDA label says

"Potentiation of epinephrine effects"

📖 Source: NLP:epinephrine 0.3 adults

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.