Does Furosemide Interact with Epoprostenol?
CDI records a minor classification for Furosemide and Epoprostenol. The stored summary is: Epoprostenol decreases furosemide clearance by 13%, but this change is not likely to be clinically significant. The mechanism involves decreased oral clearance of furosemide. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Minor
- Furosemide Class
- Loop Diuretic
- Epoprostenol Class
- Prostacycline Vasodilator
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Decreased oral clearance of furosemide
What To Tell Your Doctor or Pharmacist
If you are taking Furosemide and your doctor is considering prescribing Epoprostenol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider