Does Grapefruit Juice Interact with Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol?
CDI records a moderate classification for Grapefruit Juice and Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol. The stored summary is: CYP3A4 inhibitor that may increase plasma hormone concentrations of desogestrel and ethinyl estradiol. The mechanism involves cyp3a4 inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A4 inhibition
What To Tell Your Doctor or Pharmacist
If you are taking Grapefruit Juice and your doctor is considering prescribing Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider