Grapefruit Juice + Simvastatin Interaction

Majorinteraction on record

Description

Avoid grapefruit juice due to increased simvastatin plasma levels and risk of myopathy and rhabdomyolysis.

Mechanism

CYP3A4 inhibition increases simvastatin plasma levels

Source: NLP:simvastatin

Related drug profiles

All Grapefruit Juice interactions →All Simvastatin interactions →
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