Ketoconazole + Ciclesonide Interaction

Unknowninteraction on record

Description

In a drug interaction study, co-administration of orally inhaled ciclesonide and oral ketoconazole, a potent inhibitor of cytochrome P450 3A4, increased the exposure (AUC) of des-ciclesonide by approximately 3.6-fold at steady state, while levels of ciclesonide remained unchanged.

Source: FDA drug label - ciclesonide