Does Lisinopril And Hydrochlorothiazide Tablets Interact with Rapamycin?
Lisinopril And Hydrochlorothiazide Tablets and Rapamycin have a moderate drug interaction according to U.S. FDA drug labeling data. mTOR (mammalian target of rapamycin) inhibitors: Patients receiving coadministration of ACE inhibitor and mTOR inhibitor (e.g., temsirolimus, sirolimus, everolimus) therapy may be at increased risk for angioedema. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Lisinopril And Hydrochlorothiazide Tablets Class
- Thiazide Diuretic
- Rapamycin Class
- mTOR Inhibitor Immunosuppressant
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Lisinopril And Hydrochlorothiazide Tablets and your doctor is considering prescribing Rapamycin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider