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Does Macrolide Antibiotics Interact with Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol?

Macrolide Antibiotics and Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol have a moderate drug interaction according to U.S. FDA drug labeling data. Zinc can inhibit the absorption of certain antibiotics; take at least 2 hours apart to minimize interactions. The mechanism involves zinc inhibits antibiotic absorption. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol Class
Vitamin C
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Macrolide Antibiotics and Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol occurs because zinc inhibits antibiotic absorption. Clinically, this means zinc can inhibit the absorption of certain antibiotics; take at least 2 hours apart to minimize interactions. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.

What To Tell Your Doctor or Pharmacist

If you are taking Macrolide Antibiotics and your doctor is considering prescribing Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Macrolide Antibiotics+💊 Vitamin A Calcium Pantothenate Ascorbic Acid Cholecalciferol(Strovite One Caplets)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Vitamin C
Source
NLP:vitamin a, calcium pantothenate, ascorbic acid, cholecalciferol, .alpha.-tocopherol succinate, d-, thiamine, riboflavin, niacinamide, pyridoxine hydrochloride, folic acid, biotin, cyanocobalamin, selenium, magnesium oxide, zinc oxide, cupric sulfate, manganese, chromium, .alpha.-lipoic acid, and lutein

What this means in plain English

Zinc can inhibit the absorption of certain antibiotics; take at least 2 hours apart to minimize interactions.

What the FDA label says

"Zinc inhibits antibiotic absorption"

📖 Source: NLP:vitamin a, calcium pantothenate, ascorbic acid, cholecalciferol, .alpha.-tocopherol succinate, d-, thiamine, riboflavin, niacinamide, pyridoxine hydrochloride, folic acid, biotin, cyanocobalamin, selenium, magnesium oxide, zinc oxide, cupric sulfate, manganese, chromium, .alpha.-lipoic acid, and lutein

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.