Does Metoprolol Tartrate And Hydrochlorothiazide Interact with Insulin Human?
Metoprolol Tartrate And Hydrochlorothiazide and Insulin Human have a moderate drug interaction according to U.S. FDA drug labeling data. Hydrochlorothiazide may increase, decrease, or have no effect on insulin requirements in diabetic patients; monitoring recommended. The mechanism involves thiazide effects on glucose metabolism. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Metoprolol Tartrate And Hydrochlorothiazide Class
- Thiazide Diuretic
- Insulin Human Class
- Insulin
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Metoprolol Tartrate And Hydrochlorothiazide and Insulin Human occurs because thiazide effects on glucose metabolism. Clinically, this means hydrochlorothiazide may increase, decrease, or have no effect on insulin requirements in diabetic patients; monitoring recommended. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Metoprolol Tartrate And Hydrochlorothiazide and your doctor is considering prescribing Insulin Human (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider