Does Naproxen Oral Interact with Furosemide?
Naproxen Oral and Furosemide have a unknown drug interaction according to U.S. FDA drug labeling data. Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients. Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Naproxen Oral Class
- Nonsteroidal Anti-inflammatory Drug
- Furosemide Class
- Loop Diuretic
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Naproxen Oral and your doctor is considering prescribing Furosemide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider