Does Nicardipine Hydrochloride Interact with Digoxin?
Nicardipine Hydrochloride and Digoxin have a moderate drug interaction according to U.S. FDA drug labeling data. Nicardipine hydrochloride usually does not alter plasma levels of digoxin; however, serum digoxin levels should be evaluated after initiating concomitant therapy. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Nicardipine Hydrochloride Class
- Dihydropyridine Calcium Channel Blocker
- Digoxin Class
- Cardiac Glycoside
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Nicardipine Hydrochloride and your doctor is considering prescribing Digoxin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider