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Does Nifedipine Interact with Lopinavir And Ritonavir?

Nifedipine and Lopinavir And Ritonavir have a unknown drug interaction according to U.S. FDA drug labeling data. felodipine, nifedipine, nicardipine ↑ dihydropyridine calcium channel blockers Clinical monitoring of patients is recommended and a dose reduction of the dihydropyridine calcium channel blocker may be considered. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Nifedipine Class
Dihydropyridine Calcium Channel Blocker
Lopinavir And Ritonavir Class
Protease Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Nifedipine and your doctor is considering prescribing Lopinavir And Ritonavir (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Nifedipine(Procardia)+💊 Lopinavir And Ritonavir(Kaletra)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Dihydropyridine Calcium Channel Blocker
Drug B class
Protease Inhibitor
Source
FDA drug label - lopinavir and ritonavir

What this means in plain English

felodipine, nifedipine, nicardipine ↑ dihydropyridine calcium channel blockers Clinical monitoring of patients is recommended and a dose reduction of the dihydropyridine calcium channel blocker may be considered.

About Nifedipine and Lopinavir And Ritonavir

Nifedipine is a Dihydropyridine Calcium Channel Blocker, while Lopinavir And Ritonavir is a Protease Inhibitor. You may recognize them by the brand names Procardia and Kaletra. Both medications are taken by mouth.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.