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Does Nifedipine Interact with Trandolapril And Verapamil Hydrochloride?

Nifedipine and Trandolapril And Verapamil Hydrochloride have a unknown drug interaction according to U.S. FDA drug labeling data. Other (Trandolapril Component) No clinically significant pharmacokinetic interaction has been found between trandolapril (or its metabolites) and nifedipine. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Nifedipine Class
Dihydropyridine Calcium Channel Blocker
Trandolapril And Verapamil Hydrochloride Class
Angiotensin Converting Enzyme Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Nifedipine and your doctor is considering prescribing Trandolapril And Verapamil Hydrochloride (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Nifedipine(Procardia)+💊 Trandolapril And Verapamil Hydrochloride(Trandolapril And Verapamil Hydrochloride)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Dihydropyridine Calcium Channel Blocker
Drug B class
Angiotensin Converting Enzyme Inhibitor
Source
FDA drug label - trandolapril and verapamil hydrochloride

What this means in plain English

Other (Trandolapril Component) No clinically significant pharmacokinetic interaction has been found between trandolapril (or its metabolites) and nifedipine.

About Nifedipine and Trandolapril And Verapamil Hydrochloride

Nifedipine is a Dihydropyridine Calcium Channel Blocker, while Trandolapril And Verapamil Hydrochloride is an Angiotensin Converting Enzyme Inhibitor. Nifedipine is also sold under the brand name Procardia. Both medications are taken by mouth. Trandolapril And Verapamil Hydrochloride additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.