Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Irbesartan And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
NSAIDs can reduce diuretic and antihypertensive effects, and may cause renal impairment including acute renal failure, especially in elderly or volume-depleted patients.
Mechanism
NSAIDs reduce the diuretic, natriuretic, and antihypertensive effects of thiazide diuretics and angiotensin II receptor antagonists
Source: NLP:irbesartan and hydrochlorothiazide