Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Losartan Potassium And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
Risk of deterioration of renal function including possible acute renal failure, and reduced diuretic, natriuretic, and antihypertensive effects. Monitor renal function periodically.
Mechanism
NSAIDs reduce antihypertensive effect and may impair renal function in elderly, volume-depleted, or renally compromised patients
Source: NLP:losartan potassium and hydrochlorothiazide