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Does Norgestrel And Ethinyl Estradiol Interact with Indinavir?

Norgestrel And Ethinyl Estradiol and Indinavir have a moderate drug interaction according to U.S. FDA drug labeling data. HIV protease inhibitor may significantly increase plasma concentrations of estrogen and/or progestin. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity: Moderate
Management: Monitor for effects
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Norgestrel And Ethinyl Estradiol and your doctor is considering prescribing Indinavir (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Ask whether any dosage adjustments are needed
Never stop or change either medication without first consulting your healthcare provider

💊 Norgestrel And Ethinyl Estradiol(Low-Ogestrel)+💊 Indinavir

Severity & Interaction Details

🟡

moderate

Be aware — moderate interaction

Documented interaction with manageable risk. May require dose adjustment or monitoring.

Severity scale

MinorContra

On record

Yes

Drug A class

—

Drug B class

—

Source

NLP:norgestrel and ethinyl estradiol

What this means in plain English

HIV protease inhibitor may significantly increase plasma concentrations of estrogen and/or progestin.

About Norgestrel And Ethinyl Estradiol and Indinavir

Norgestrel And Ethinyl Estradiol is also sold under the brand name Low-Ogestrel. Norgestrel And Ethinyl Estradiol is taken by mouth. Norgestrel And Ethinyl Estradiol additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Recent research & FDA safety updates

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Auto-aggregated from PubMed E-utilities and FDA safety data.

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Predictive modeling of influenza strain drugs using temperature-based topological indices and regression analysis via multi-criteria decision making techniques.about Indinavir · 2026-03

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From virtual screening to animal models: chlorhexidine and indinavir as promising anti-Zika drug candidates.about Indinavir · 2026-01

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Structure-based drug repurposing and experimental validation of inhibitors targeting LigaseD from Mycobacterium tuberculosis.about Indinavir · 2026-01

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.