Does Olmesartan Medoxomil And Amlodipine Besylate And Hydrochloro Interact with Amlodipine?
Olmesartan Medoxomil And Amlodipine Besylate And Hydrochloro and Amlodipine have a moderate drug interaction according to U.S. FDA drug labeling data. Amlodipine ( 7.2 ): • Limit simvastatin to 20 mg daily when coadministered. • Increased exposure to cyclosporin and tacrolimus • Increased amlodipine exposure when coadministered with CYP3A inhibitors Hydrochlorothiazide ( 7.3 ): • Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. Closely monitor blood pressure, renal function and electrolytes in patients on olmesartan medoxomil, amlodipine, and hydrochlorothiazide tablets and other agents that affect the RAS. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Olmesartan Medoxomil And Amlodipine Besylate And Hydrochloro Class
- Thiazide Diuretic
- Amlodipine Class
- Dihydropyridine Calcium Channel Blocker
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Olmesartan Medoxomil And Amlodipine Besylate And Hydrochloro and your doctor is considering prescribing Amlodipine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider