Does Paclitaxel Interact with Bevacizumab Maly?
Paclitaxel and Bevacizumab Maly have a moderate drug interaction according to U.S. FDA drug labeling data. No clinically meaningful overall effect on pharmacokinetics; however, 3 of 8 patients receiving bevacizumab with paclitaxel and carboplatin had lower paclitaxel exposure at Day 63 compared to Day 0. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Paclitaxel Class
- Microtubule Inhibitor
- Bevacizumab Maly Class
- Vascular Endothelial Growth Factor Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Paclitaxel and your doctor is considering prescribing Bevacizumab Maly (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider