Phenobarbital Sodium + Doxycycline Interaction

Unknowninteraction on record

Description

Doxycycline Phenobarbital has been shown to shorten the half-life of doxycycline for as long as 2 weeks after barbiturate therapy is discontinued. If phenobarbital and doxycycline are administered concurrently, the clinical response to doxycycline should be monitored closely.

Source: FDA drug label - phenobarbital sodium