Does Posaconazole Interact with Efavirenz Lamivudine And Tenofovir Disoproxil Fumarate?
Posaconazole and Efavirenz Lamivudine And Tenofovir Disoproxil Fumarate have a major drug interaction according to U.S. FDA drug labeling data. Posaconazole ↓ posaconazole Avoid concomitant use unless the benefit outweighs the risks. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Major
- Posaconazole Class
- Azole Antifungal
- Efavirenz Lamivudine And Tenofovir Disoproxil Fumarate Class
- Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Posaconazole and your doctor is considering prescribing Efavirenz Lamivudine And Tenofovir Disoproxil Fumarate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider