Prasugrel + Ketoconazole Interaction

Unknowninteraction on record

Description

Drug Interaction Studies Potential for Other Drugs to Affect Prasugrel Inhibitors of CYP3A Ketoconazole (400 mg daily), a selective and potent inhibitor of CYP3A4 and CYP3A5, did not affect prasugrel-mediated inhibition of platelet aggregation or the active metabolite’s AUC and T max , but decreased the C max by 34% to 46%.

Source: FDA drug label - prasugrel