Does Quinapril Hydrochloride Interact with Cimetidine?
Quinapril Hydrochloride and Cimetidine have a minor drug interaction according to U.S. FDA drug labeling data. Multiple dose therapy with cimetidine has no effect on the pharmacokinetics of single doses of quinapril. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Cimetidine Class
- Histamine-2 Receptor Antagonist
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Quinapril Hydrochloride and your doctor is considering prescribing Cimetidine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider