Quinidine + Metoprolol Tartrate And Hydrochlorothiazide Interaction

Moderateinteraction on record

Description

Strong CYP2D6 inhibitor that doubles metoprolol concentrations and decreases cardioselectivity. Monitor patients closely when combination cannot be avoided.

Mechanism

CYP2D6 inhibition

Source: NLP:metoprolol tartrate and hydrochlorothiazide