Does Ramipril Interact with Telmisartan And Amlodipine?
CDI records a moderate classification for Ramipril and Telmisartan And Amlodipine. The stored summary is: Co-administration increases steady-state Cmax and AUC of ramipril and ramiprilat (2.3-2.4 fold and 2.1-1.5 fold respectively) with additive pharmacodynamic effects possible. The mechanism involves increased ramipril and ramiprilat exposure with additive pharmacodynamic effects. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Ramipril Class
- Angiotensin Converting Enzyme Inhibitor
- Telmisartan And Amlodipine Class
- Angiotensin 2 Receptor Blocker
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Increased ramipril and ramiprilat exposure with additive pharmacodynamic effects
What To Tell Your Doctor or Pharmacist
If you are taking Ramipril and your doctor is considering prescribing Telmisartan And Amlodipine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider