Rifabutin + Indinavir Interaction
Unknowninteraction on record
Description
Indinavir 800 mg three times a day for 10 days 300 mg once a day for 10 days Healthy subjects (10) ↑ AUC by 173%, ↑ C max by 134% ↓ AUC by 34%, ↓ C max by 25%, ↓ C min by 39% Reduce rifabutin dose by 50%, and increase indinavir dose from 800 mg to 1000 mg three times a day.
Source: FDA drug label - rifabutin