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Does Ritonavir 100 Mg Interact with Diazepam?

Ritonavir 100 Mg and Diazepam have a unknown drug interaction according to U.S. FDA drug labeling data. Sedative/hypnotics: buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem ↑ sedative/hypnotics A dose decrease may be needed for these drugs when co-administered with ritonavir. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Ritonavir 100 Mg Class
Cytochrome P450 3A Inhibitor
Diazepam Class
Benzodiazepine
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ritonavir 100 Mg and your doctor is considering prescribing Diazepam (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ritonavir 100 Mg(Ritonavir Film Coated)+💊 Diazepam(Valium)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Cytochrome P450 3A Inhibitor
Drug B class
Benzodiazepine
Source
FDA drug label - ritonavir 100 mg

What this means in plain English

Sedative/hypnotics: buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem ↑ sedative/hypnotics A dose decrease may be needed for these drugs when co-administered with ritonavir.

About Ritonavir 100 Mg and Diazepam

Ritonavir 100 Mg is a Cytochrome P450 3A Inhibitor, while Diazepam is a Benzodiazepine. Diazepam is also sold under the brand name Valium. Both medications are taken by mouth. Both Ritonavir 100 Mg and Diazepam carry an FDA boxed warning — the agency's most serious safety designation.

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Check Ritonavir 100 Mg and Diazepam against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.