HomeRitonavir 100 MgRitonavir 100 Mg + Rifampin

Does Ritonavir 100 Mg Interact with Rifampin?

Ritonavir 100 Mg and Rifampin have a contraindicated drug interaction according to U.S. FDA drug labeling data. Saquinavir/ritonavir combination with rifampin is not recommended. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Ritonavir 100 Mg Class
Cytochrome P450 3A Inhibitor
Rifampin Class
Rifamycin Antibacterial
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ritonavir 100 Mg and your doctor is considering prescribing Rifampin (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ritonavir 100 Mg(Ritonavir Film Coated)+💊 Rifampin(Rifampin)

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Cytochrome P450 3A Inhibitor
Drug B class
Rifamycin Antibacterial
Source
NLP:ritonavir 100 mg

What this means in plain English

Saquinavir/ritonavir combination with rifampin is not recommended.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.