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Does Ritonavir Interact with Telmisartan And Amlodipine?

Ritonavir and Telmisartan And Amlodipine have a unknown drug interaction according to U.S. FDA drug labeling data. However, strong inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, ritonavir) may increase the plasma concentrations of amlodipine to a greater extent. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Ritonavir Class
Cytochrome P450 3A Inhibitor
Telmisartan And Amlodipine Class
Angiotensin 2 Receptor Blocker
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ritonavir and your doctor is considering prescribing Telmisartan And Amlodipine (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ritonavir(Norvir)+💊 Telmisartan And Amlodipine(Twynsta)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Cytochrome P450 3A Inhibitor
Drug B class
Angiotensin 2 Receptor Blocker
Source
FDA drug label - telmisartan and amlodipine

What this means in plain English

However, strong inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, ritonavir) may increase the plasma concentrations of amlodipine to a greater extent.

About Ritonavir and Telmisartan And Amlodipine

Ritonavir is a Cytochrome P450 3A Inhibitor, while Telmisartan And Amlodipine is an Angiotensin 2 Receptor Blocker. You may recognize them by the brand names Norvir and Twynsta. Both medications are taken by mouth. Both Ritonavir and Telmisartan And Amlodipine carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.