Salicylates + Liothyronine Sodium Interaction
Moderateinteraction on record
Description
At doses >2 g/day, salicylates inhibit binding of T4 and T3 to TBG and transthyretin, with initial increase in serum FT4 followed by normalization. Total T4 levels may decrease by up to 30%. Closely monitor thyroid parameters.
Mechanism
Inhibition of T4 and T3 binding to TBG and transthyretin
Source: NLP:liothyronine sodium