Segesterone Acetate And Ethinyl Estradiol + Miconazole Interaction

Unknowninteraction on record

Description

7.3 Use of Vaginal Products with ANNOVERA In a drug-drug interaction study with ANNOVERA and the concurrent use of three different formulations of vaginal miconazole, the use of water-based vaginal miconazole cream resulted in no change in exposure to EE or SA from the vaginal system. However, the use of either the 1- day or the 3-day oil-based miconazole suppository was associated with an overall increase in exposure up to 67% for EE and 32% for SA.

Source: FDA drug label - segesterone acetate and ethinyl estradiol