Does Selective Serotonin Reuptake Inhibitors Ssri Interact with Naproxen Oral?
CDI records a moderate classification for Selective Serotonin Reuptake Inhibitors Ssri and Naproxen Oral. The stored summary is: Concomitant use may potentiate bleeding risk more than naproxen alone due to serotonin reuptake interference. The mechanism involves serotonin reuptake inhibition impairs platelet hemostasis. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Naproxen Oral Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Serotonin reuptake inhibition impairs platelet hemostasis
What To Tell Your Doctor or Pharmacist
If you are taking Selective Serotonin Reuptake Inhibitors Ssri and your doctor is considering prescribing Naproxen Oral (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider