HomeSitagliptin And Metformin HydrochlorideSitagliptin And Metformin Hydrochloride + Insulin Human

Does Sitagliptin And Metformin Hydrochloride Interact with Insulin Human?

Sitagliptin And Metformin Hydrochloride and Insulin Human have a major drug interaction according to U.S. FDA drug labeling data. Increases hypoglycemia risk when combined with ZITUVIMET XR; may require dose reduction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Sitagliptin And Metformin Hydrochloride Class
Dipeptidyl Peptidase 4 Inhibitor
Insulin Human Class
Insulin
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Sitagliptin And Metformin Hydrochloride and your doctor is considering prescribing Insulin Human (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Sitagliptin And Metformin Hydrochloride(Janumet)+💊 Insulin Human(Myxredlin)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
Dipeptidyl Peptidase 4 Inhibitor
Drug B class
Insulin
Source
NLP:sitagliptin and metformin hydrochloride

What this means in plain English

Increases hypoglycemia risk when combined with ZITUVIMET XR; may require dose reduction.

About Sitagliptin And Metformin Hydrochloride and Insulin Human

Sitagliptin And Metformin Hydrochloride is a Dipeptidyl Peptidase 4 Inhibitor, while Insulin Human is an Insulin. You may recognize them by the brand names Janumet and Myxredlin. Sitagliptin And Metformin Hydrochloride is taken by mouth, whereas Insulin Human is given by intravenous (IV) infusion. Both Sitagliptin And Metformin Hydrochloride and Insulin Human carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.