St. John'S Wort + Norgestimate And Ethinyl Estradiol Interaction

Moderateinteraction on record

Description

Herbal product that induces CYP3A4 and may decrease plasma concentrations of COCs and potentially diminish contraceptive effectiveness or increase breakthrough bleeding.

Mechanism

CYP3A4 enzyme induction

Source: NLP:norgestimate and ethinyl estradiol