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Does Succinylcholine Chloride Interact with Quinine?

Succinylcholine Chloride and Quinine have a major drug interaction according to U.S. FDA drug labeling data. May enhance the neuromuscular blocking action of succinylcholine. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity: Major
Management: Close medical supervision required
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Succinylcholine Chloride and your doctor is considering prescribing Quinine (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Ask how frequently you should be monitored while these are co-prescribed
Ask whether any dosage adjustments are needed
Never stop or change either medication without first consulting your healthcare provider

💊 Succinylcholine Chloride(Quelicin)+💊 Quinine(Quinine Sulfate)

Severity & Interaction Details

⚠️

major

Use with caution — major interaction

Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.

Severity scale

MinorContra

On record

Yes

Drug A class

—

Drug B class

—

Source

NLP:succinylcholine chloride

What this means in plain English

May enhance the neuromuscular blocking action of succinylcholine.

About Succinylcholine Chloride and Quinine

Succinylcholine Chloride is also sold under the brand name Quelicin. Succinylcholine Chloride is given by intramuscular injection, whereas Quinine is taken by mouth. Both Succinylcholine Chloride and Quinine carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.