HomeTelmisartan And HydrochlorothiazideTelmisartan And Hydrochlorothiazide + Telmisartan

Does Telmisartan And Hydrochlorothiazide Interact with Telmisartan?

Telmisartan And Hydrochlorothiazide and Telmisartan have a major drug interaction according to U.S. FDA drug labeling data. Drug Interactions Telmisartan Aliskiren: Do not co-administer aliskiren with telmisartan and hydrochlorothiazide tablets in patients with diabetes. Avoid use of aliskiren with telmisartan and hydrochlorothiazide tablets in patients with renal impairment (GFR <60 mL/min). Digoxin : When telmisartan was co-administered with digoxin, median increases in digoxin peak plasma concentration (49%) and in trough concentration (20%) were observed. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Telmisartan And Hydrochlorothiazide Class
Angiotensin 2 Receptor Blocker
Telmisartan Class
Angiotensin 2 Receptor Blocker
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Telmisartan And Hydrochlorothiazide and your doctor is considering prescribing Telmisartan (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Telmisartan And Hydrochlorothiazide(Micardis-HCT)+💊 Telmisartan(Twynsta)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
Angiotensin 2 Receptor Blocker
Drug B class
Angiotensin 2 Receptor Blocker
Source
FDA drug label - telmisartan and hydrochlorothiazide

What this means in plain English

Drug Interactions Telmisartan Aliskiren: Do not co-administer aliskiren with telmisartan and hydrochlorothiazide tablets in patients with diabetes. Avoid use of aliskiren with telmisartan and hydrochlorothiazide tablets in patients with renal impairment (GFR <60 mL/min). Digoxin : When telmisartan was co-administered with digoxin, median increases in digoxin peak plasma concentration (49%) and in trough concentration (20%) were observed.

About Telmisartan And Hydrochlorothiazide and Telmisartan

Telmisartan And Hydrochlorothiazide and Telmisartan both belong to the Angiotensin 2 Receptor Blocker class. You may recognize them by the brand names Micardis-HCT and Twynsta. Both medications are taken by mouth. Both Telmisartan And Hydrochlorothiazide and Telmisartan carry an FDA boxed warning — the agency's most serious safety designation.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Telmisartan And Hydrochlorothiazide and Telmisartan against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.