Does Teriflunomide Interact with Furosemide?
CDI records a moderate classification for Teriflunomide and Furosemide. The stored summary is: Teriflunomide may increase exposure of furosemide. Monitor patients and adjust dose as required. The mechanism involves oat3 inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
Evidence status
A current label comparison is not yet available for this record. The summary and severity are stored CDI information; they have not been independently validated on this page against the exact product label.
Confirm the medicine, formulation, route, and applicable warning with your pharmacist or prescriber. Independent clinical review has not been recorded.
- Stored CDI classification
- Moderate
- Teriflunomide Class
- Pyrimidine Synthesis Inhibitor
- Furosemide Class
- Loop Diuretic
- Management
- Confirm exact products with your pharmacist
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
OAT3 inhibition
What To Tell Your Doctor or Pharmacist
If you are taking Teriflunomide and your doctor is considering prescribing Furosemide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider