HomeTezacaftor And IvacaftorTezacaftor And Ivacaftor + Ciprofloxacin

Does Tezacaftor And Ivacaftor Interact with Ciprofloxacin?

Tezacaftor And Ivacaftor and Ciprofloxacin have a minor drug interaction according to U.S. FDA drug labeling data. No significant effect on tezacaftor or ivacaftor exposure; no dosage adjustment necessary. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Minor
Ciprofloxacin Class
Fluoroquinolone Antibacterial
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Tezacaftor And Ivacaftor and your doctor is considering prescribing Ciprofloxacin (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Tezacaftor And Ivacaftor(Symdeko)+💊 Ciprofloxacin(Otovel)

Severity & Interaction Details

minor
Generally safe — minor interaction
Low clinical significance. Routine awareness is usually sufficient.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Fluoroquinolone Antibacterial
Source
NLP:tezacaftor and ivacaftor

What this means in plain English

No significant effect on tezacaftor or ivacaftor exposure; no dosage adjustment necessary.

About Tezacaftor And Ivacaftor and Ciprofloxacin

Ciprofloxacin is a Fluoroquinolone Antibacterial. You may recognize them by the brand names Symdeko and Otovel. Ciprofloxacin is taken by mouth. Ciprofloxacin additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.