Does Theophylline Interact with Butorphanol Tartrate?
Theophylline and Butorphanol Tartrate have a unknown drug interaction according to U.S. FDA drug labeling data. CYP450 inducer; effects on butorphanol metabolism unknown; smaller initial dose and longer dosing intervals may be needed. The mechanism involves cyp450 metabolism induction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Theophylline Class
- Methylxanthine
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Theophylline and Butorphanol Tartrate occurs because cyp450 metabolism induction. Clinically, this means cyp450 inducer; effects on butorphanol metabolism unknown; smaller initial dose and longer dosing intervals may be needed.
What To Tell Your Doctor or Pharmacist
If you are taking Theophylline and your doctor is considering prescribing Butorphanol Tartrate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider