Does Ticagrelor Interact with Morphine?
CDI records a major classification for Ticagrelor and Morphine. The stored summary is: Opioid agonist delays and reduces absorption of ticagrelor and its active metabolite through slowed gastric emptying. The mechanism involves delayed gastric emptying. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Ticagrelor Class
- P2Y12 Platelet Inhibitor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Delayed gastric emptying
What To Tell Your Doctor or Pharmacist
If you are taking Ticagrelor and your doctor is considering prescribing Morphine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider