Topical Local Anesthetics + Methadone Hydrochloride Interaction

Majorinteraction on record

Description

CNS depressant effect increases risk of respiratory depression, profound sedation, coma, and death.

Mechanism

Additive pharmacologic effect

Source: NLP:methadone hydrochloride

Related drug profiles

All Topical Local Anesthetics interactions →All Methadone Hydrochloride interactions →
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