Does Trandolapril And Verapamil Hydrochloride Interact with Rapamycin?
Trandolapril And Verapamil Hydrochloride and Rapamycin have a moderate drug interaction according to U.S. FDA drug labeling data. Mammalian Target of Rapamycin (mTOR) Inhibitors Patients taking concomitant mTOR inhibitor (e.g., temsirolimus, sirolimus, everolimus) therapy may be at increased risk for angioedema (see WARNINGS - Angioedema ). Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Trandolapril And Verapamil Hydrochloride Class
- Angiotensin Converting Enzyme Inhibitor
- Rapamycin Class
- mTOR Inhibitor Immunosuppressant
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Trandolapril And Verapamil Hydrochloride and your doctor is considering prescribing Rapamycin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider