Does Valproic Acid Interact with Aspirin And Extended Release Dipyridamole?
CDI records a moderate classification for Valproic Acid and Aspirin And Extended Release Dipyridamole. The stored summary is: Salicylic acid can displace protein-bound valproic acid, leading to increased serum levels. The mechanism involves displacement from protein binding. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Valproic Acid Class
- Anti-epileptic Agent
- Aspirin And Extended Release Dipyridamole Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Displacement from protein binding
What To Tell Your Doctor or Pharmacist
If you are taking Valproic Acid and your doctor is considering prescribing Aspirin And Extended Release Dipyridamole (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider