Does Warfarin Interact with Glecaprevir And Pibrentasvir?
CDI records a moderate classification for Warfarin and Glecaprevir And Pibrentasvir. The stored summary is: Clearance of HCV infection may alter hepatic function and impact INR. Frequent monitoring of INR and dose adjustments may be necessary. The mechanism involves changes in hepatic function after hcv clearance. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Glecaprevir And Pibrentasvir Class
- Hepatitis C Virus NS5A Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Changes in hepatic function after HCV clearance
What To Tell Your Doctor or Pharmacist
If you are taking Warfarin and your doctor is considering prescribing Glecaprevir And Pibrentasvir (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider