Does Warfarin Interact with Soybean Oil?
CDI records a moderate classification for Warfarin and Soybean Oil. The stored summary is: Soybean oil contains vitamin K1 which can reverse the anticoagulant activity of warfarin. Monitor laboratory parameters for anticoagulant activity. The mechanism involves vitamin k1 in soybean oil reverses anticoagulant activity by interfering with coumarin derivatives' mechanism of blocking vitamin k recycling. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Soybean Oil Class
- Lipid Emulsion
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Vitamin K1 in soybean oil reverses anticoagulant activity by interfering with coumarin derivatives' mechanism of blocking vitamin K recycling
What To Tell Your Doctor or Pharmacist
If you are taking Warfarin and your doctor is considering prescribing Soybean Oil (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider