Home›Ziprasidone Hcl›Ziprasidone Hcl + Progesterone

Does Ziprasidone Hcl Interact with Progesterone?

Ziprasidone Hcl and Progesterone have a unknown drug interaction according to U.S. FDA drug labeling data. 7.6 Oral Contraceptives In vivo studies have revealed no effect of ziprasidone on the pharmacokinetics of estrogen or progesterone components. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity: Unknown
Ziprasidone Hcl Class: Atypical Antipsychotic
Progesterone Class: Progesterone
Management: Consult your pharmacist
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ziprasidone Hcl and your doctor is considering prescribing Progesterone (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Never stop or change either medication without first consulting your healthcare provider

💊 Ziprasidone Hcl(Ziprasidone Hydrochloride)+💊 Progesterone(Eazi-Breed CIDR)

Severity & Interaction Details

ℹ️

unknown

Interaction documented — severity unclassified

The FDA label notes an interaction but the severity is not classified in our dataset.

Severity scale

MinorContra

On record

Yes

Drug A class

Atypical Antipsychotic

Drug B class

Progesterone

Source

FDA drug label - ziprasidone hcl

What this means in plain English

7.6 Oral Contraceptives In vivo studies have revealed no effect of ziprasidone on the pharmacokinetics of estrogen or progesterone components.

About Ziprasidone Hcl and Progesterone

Ziprasidone Hcl is an Atypical Antipsychotic, while Progesterone is a Progesterone. Progesterone is also sold under the brand name Eazi-Breed CIDR. Both medications are taken by mouth. Both Ziprasidone Hcl and Progesterone carry an FDA boxed warning — the agency's most serious safety designation.

Recent research & FDA safety updates

Live

Auto-aggregated from PubMed E-utilities and FDA safety data.

FDA

FDA Safety Alert: Accucaine, Kit contains: Lidocaine HCl Injection USP, 1% (10 mg/mL), 5 mL single dose ampule, Rx Onlabout Ziprasidone Hcl · 2026-07

Share this result:

WhatsApp Text / SMS Email

Also share on:X Facebook

Add more drugs

Check Ziprasidone Hcl and Progesterone against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.