alfuzosin and ritonavir: what the product label says

The product label for alfuzosin names ritonavir in its drug-interaction information. The complete selected section is reproduced below so that qualifications stay with the finding.

Which products this evidence covers

Alfuzosin Hydrochloride — TABLET, EXTENDED RELEASE — ORAL

Labeled active ingredients: ALFUZOSIN HYDROCHLORIDE; ALFUZOSIN. Routes: ORAL. Dosage forms: TABLET, EXTENDED RELEASE.

Supporting label passage

Section: 5.4 Drug-Drug Interactions

Potent CYP3A4 Inhibitors Alfuzosin hydrochloride extended-release tablets are contraindicated for use with potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) since alfuzosin blood levels are increased [ see Contraindications ( 4 ), Drug Interactions ( 7.1 ) and Clinical Pharmacology ( 12.3) ]. Other alpha-adrenergic antagonists Alfuzosin hydrochloride extended-release tablets are an alpha-adrenergic antagonist and should not be used in combination with other alpha adrenergic antagonist [ see Drug Interactions ( 7.2 ) ]. Phosphodiesterase-5 (PDE5) Inhibitors PDE5-inhibitors are also vasodilators. Caution is advised for concomitant use of PDE5-inhibitors and alfuzosin hydrochloride extended-release tablets, as this combination can potentially cause symptomatic hypotension [ see Drug Interactions ( 7.4) ].

Read the full product label on DailyMed. Label version 18, dated 2026-09-03.

Limits of this evidence

This passage applies to the labeled product and circumstances it describes. It must not be generalized to other routes or formulations. It does not independently validate CDI’s severity category, establish safety for an individual, or replace the full label. The stored interaction description and classification have not been changed by this article.

How this brief was prepared

Automatic checks matched drug identities, retrieved and preserved the label, and checked the full quoted section with AI assistance on 2026-10-28. The public explanation uses a fixed template; model-written medical advice is not published. Independent clinical review has not been recorded.

Discuss your exact medicines with your pharmacist

Ask your pharmacist or prescriber whether the cited products, routes and circumstances apply to your medicines before changing treatment.

Check your medication list with CDI.