apomorphine and ondansetron: what the product label says

The product label for apomorphine names ondansetron in its drug-interaction information. The complete selected section is reproduced below so that qualifications stay with the finding.

Which products this evidence covers

ONAPGO — INJECTION, SOLUTION — SUBCUTANEOUS

Labeled active ingredients: APOMORPHINE HYDROCHLORIDE; APOMORPHINE. Routes: SUBCUTANEOUS. Dosage forms: INJECTION, SOLUTION.

Supporting label passage

Section: 7.1 5HT 3 Antagonists

Based on reports of profound hypotension and loss of consciousness when apomorphine was administered with ondansetron, the concomitant use of ONAPGO with 5HT 3 antagonists, including antiemetics (e.g., ondansetron, granisetron, palonosetron) and alosetron, is contraindicated [see Warnings and Precautions (5.4) ].

Read the full product label on DailyMed. Label version 21, dated 2026-10-05.

Limits of this evidence

This passage applies to the labeled product and circumstances it describes. It must not be generalized to other routes or formulations. It does not independently validate CDI’s severity category, establish safety for an individual, or replace the full label. The stored interaction description and classification have not been changed by this article.

How this brief was prepared

Automatic checks matched drug identities, retrieved and preserved the label, and checked the full quoted section with AI assistance on 2026-11-06. The public explanation uses a fixed template; model-written medical advice is not published. Independent clinical review has not been recorded.

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