Home›Thyroid Hormones

Thyroid Hormones

23 interactions on record

Thyroid Hormones has 23 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Epinephrine, Epinephrine In Sodium Chloride, Insulin Glargine. Patients taking Thyroid Hormones should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 23
Major: 4
Moderate: 17
Minor: 2

Major (4)

Thyroid Hormones + Epinephrine— Potentiate arrhythmogenic effects of epinephrine; observe carefully for cardiac arrhythmias.
Thyroid Hormones + Epinephrine In Sodium Chloride— Increase arrhythmogenic potential of epinephrine. Monitor for cardiac arrhythmias.
Thyroid Hormones + Insulin Glargine— May decrease blood glucose lowering effect of LANTUS. Dosage increases and increased glucose monitoring may be required.
Thyroid Hormones + Midodrine Hydrochloride— Increases risk of hypertension when used concomitantly with midodrine. Avoid concomitant use or monitor blood pressure c…

Moderate (17)

Thyroid Hormones + Estradiol— Estradiol increases thyroid-binding globulin, which may increase circulating total thyroid hormone levels. Patients on t…
Thyroid Hormones + Glimepiride— May reduce glucose-lowering effect of glimepiride, leading to worsening glycemic control.
Thyroid Hormones + Glipizide— May reduce the glucose-lowering effect of glipizide, leading to worsening glycemic control. Monitor closely.
Thyroid Hormones + Insulin Aspart Injection— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Aspart-Szjj— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Degludec— May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Degludec And Liraglutide— May decrease blood glucose-lowering effect; dosage increases and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Detemir— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Thyroid Hormones + Insulin Glargine And Lixisenatide— May decrease the blood glucose lowering effect. Dose increases and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Glargine-Aglr— May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Glargine-Yfgn— May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Glulisine— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Human— May decrease blood glucose lowering effect; dose adjustment and increased glucose monitoring may be required.
Thyroid Hormones + Insulin Lispro— May decrease the blood glucose lowering effect. Dose adjustment and increased frequency of glucose monitoring may be req…
Thyroid Hormones + Insulin Lispro-Aabc— May decrease blood glucose lowering effect. Dose increases and increased glucose monitoring may be required.
Thyroid Hormones + Norethindrone Acetate, Ethinyl Estradiol And Ferrous Fumarate— Women on thyroid hormone replacement may need increased doses because serum concentration of thyroid-binding globulin in…
Thyroid Hormones + Norethindrone Acetate/Ethinyl Estradiol— Women on thyroid hormone replacement therapy may need increased doses due to increased serum thyroid-binding globulin wi…

Minor (2)

Thyroid Hormones + Montelukast— No dose adjustment needed when co-administered with montelukast sodium.
Thyroid Hormones + Montelukast Sodium— No dose adjustment needed when co-administered with montelukast sodium.

Thyroid Hormones + Epinephrine⚠️Major

Potentiate arrhythmogenic effects of epinephrine; observe carefully for cardiac arrhythmias.

Thyroid Hormones + Epinephrine In Sodium Chloride⚠️Major

Increase arrhythmogenic potential of epinephrine. Monitor for cardiac arrhythmias.

Thyroid Hormones + Insulin Glargine⚠️Major

May decrease blood glucose lowering effect of LANTUS. Dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Midodrine Hydrochloride⚠️Major

Increases risk of hypertension when used concomitantly with midodrine. Avoid concomitant use or monitor blood pressure closely.

Thyroid Hormones + Estradiol🟡Moderate

Estradiol increases thyroid-binding globulin, which may increase circulating total thyroid hormone levels. Patients on thyroid replacement therapy may require higher doses.

Thyroid Hormones + Glimepiride🟡Moderate

May reduce glucose-lowering effect of glimepiride, leading to worsening glycemic control.

Thyroid Hormones + Glipizide🟡Moderate

May reduce the glucose-lowering effect of glipizide, leading to worsening glycemic control. Monitor closely.

Thyroid Hormones + Insulin Aspart Injection🟡Moderate

May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Aspart-Szjj🟡Moderate

May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Degludec🟡Moderate

May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Degludec And Liraglutide🟡Moderate

May decrease blood glucose-lowering effect; dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Detemir🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Glargine And Lixisenatide🟡Moderate

May decrease the blood glucose lowering effect. Dose increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Glargine-Aglr🟡Moderate

May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Glargine-Yfgn🟡Moderate

May decrease blood glucose lowering effect. Dosage increases and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Glulisine🟡Moderate

May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Human🟡Moderate

May decrease blood glucose lowering effect; dose adjustment and increased glucose monitoring may be required.

Thyroid Hormones + Insulin Lispro🟡Moderate

May decrease the blood glucose lowering effect. Dose adjustment and increased frequency of glucose monitoring may be required.

Thyroid Hormones + Insulin Lispro-Aabc🟡Moderate

May decrease blood glucose lowering effect. Dose increases and increased glucose monitoring may be required.

Thyroid Hormones + Norethindrone Acetate, Ethinyl Estradiol And Ferrous Fumarate🟡Moderate

Women on thyroid hormone replacement may need increased doses because serum concentration of thyroid-binding globulin increases with COC use.

Thyroid Hormones + Norethindrone Acetate/Ethinyl Estradiol🟡Moderate

Women on thyroid hormone replacement therapy may need increased doses due to increased serum thyroid-binding globulin with COC use.

Thyroid Hormones + Montelukast🟢Minor

No dose adjustment needed when co-administered with montelukast sodium.

Thyroid Hormones + Montelukast Sodium🟢Minor

No dose adjustment needed when co-administered with montelukast sodium.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.