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Dicloenac Sodium And Misoprostol

Also known as: Dicloenac Sodium And Misoprostol Dr

Prostaglandin E1 Analog

Route: Oral

Check Dicloenac Sodium And Misoprostol Interactions →

6 interactions on record⛔ Black Box Warning

Dicloenac Sodium And Misoprostol has 6 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Aspirin, Warfarin, Angiotensin Ii. Patients taking Dicloenac Sodium And Misoprostol should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 6
Major: 2
Moderate: 3

Major (2)

Dicloenac Sodium And Misoprostol + Aspirin— Increased incidence of GI adverse reactions and increased risk of bleeding. Concomitant use not generally recommended at…
Dicloenac Sodium And Misoprostol + Warfarin— Synergistic effect on bleeding with increased risk of serious bleeding compared to either drug alone.

Moderate (3)

Dicloenac Sodium And Misoprostol + Angiotensin Ii— NSAIDs may diminish antihypertensive effect and may result in deterioration of renal function, especially in elderly, vo…
Dicloenac Sodium And Misoprostol + Mao Inhibitors— NSAIDs may diminish antihypertensive effect and may result in deterioration of renal function, especially in elderly, vo…
Dicloenac Sodium And Misoprostol + Propranolol— NSAIDs may diminish the antihypertensive effect of beta-blockers. Monitor blood pressure during concomitant use.

Dicloenac Sodium And Misoprostol + Aspirin⚠️Major

Increased incidence of GI adverse reactions and increased risk of bleeding. Concomitant use not generally recommended at analgesic doses.

Dicloenac Sodium And Misoprostol + Warfarin⚠️Major

Synergistic effect on bleeding with increased risk of serious bleeding compared to either drug alone.

Dicloenac Sodium And Misoprostol + Angiotensin Ii🟡Moderate

NSAIDs may diminish antihypertensive effect and may result in deterioration of renal function, especially in elderly, volume-depleted, or renally impaired patients.

Dicloenac Sodium And Misoprostol + Mao Inhibitors🟡Moderate

NSAIDs may diminish antihypertensive effect and may result in deterioration of renal function, especially in elderly, volume-depleted, or renally impaired patients.

Dicloenac Sodium And Misoprostol + Propranolol🟡Moderate

NSAIDs may diminish the antihypertensive effect of beta-blockers. Monitor blood pressure during concomitant use.

Dicloenac Sodium And Misoprostol + Furosemideℹ️Unknown

Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.