Does Dicloenac Sodium And Misoprostol Interact with Angiotensin Ii?
CDI records a moderate classification for Dicloenac Sodium And Misoprostol and Angiotensin Ii. The stored summary is: NSAIDs may diminish antihypertensive effect and may result in deterioration of renal function, especially in elderly, volume-depleted, or renally impaired patients. The mechanism involves diminished antihypertensive effect and renal function deterioration. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Dicloenac Sodium And Misoprostol Class
- Prostaglandin E1 Analog
- Angiotensin Ii Class
- Vasoconstrictor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Diminished antihypertensive effect and renal function deterioration
What To Tell Your Doctor or Pharmacist
If you are taking Dicloenac Sodium And Misoprostol and your doctor is considering prescribing Angiotensin Ii (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider