Cholic Acid has 7 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Cyclosporine, Antacids Containing Aluminum, Cholestyramine Light. Patients taking Cholic Acid should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 7
- Major
- 1
- Moderate
- 6
Major (1)
- Cholic Acid + Cyclosporine— BSEP inhibitor that may exacerbate accumulation of conjugated bile salts in liver. Avoid concomitant use; if necessary, …
Moderate (6)
- Cholic Acid + Antacids Containing Aluminum— Aluminum-based antacids adsorb bile acids in vitro and reduce CHOLBAM availability. Take CHOLBAM at least 1 hour before …
- Cholic Acid + Cholestyramine Light— Bile acid binding resin that adsorbs and reduces bile acid absorption, potentially reducing CHOLBAM efficacy. Take CHOLB…
- Cholic Acid + Colesevelam— Bile acid binding resin that adsorbs and reduces bile acid absorption, potentially reducing CHOLBAM efficacy. Take CHOLB…
- Cholic Acid + Colestipol— Bile acid binding resin that adsorbs and reduces bile acid absorption, potentially reducing CHOLBAM efficacy. Take CHOLB…
- Cholic Acid + Fenofibrate— Bile-acid binding resins may bind fenofibrate given concurrently, impeding its absorption.
- Cholic Acid + Fenofibric Acid— Bile-acid binding resins may bind fenofibric acid concurrently. Administer fenofibric acid at least 1 hour before or 4-6…